--- title: "Projects | Mike Sinn" description: "10 open-source projects that each started as \"a quick prototype\" and evolved into \"my personality now.\"" url: https://mikesinn.com/projects --- # Projects Software built instead of going to therapy. Each project started as "a quick prototype" and evolved into "my personality now." 10K+ PARTICIPANTS 12M+ DATA POINTS 50K+ STUDIES PUBLISHED CAUSAL INFERENCE ### Optimitron An open-source platform that uses causal inference to figure out which policies actually save lives instead of just sounding good at press conferences. Analyzed 11 natural experiments and 14 policy areas across 50+ years. Found that Singapore gets better health outcomes at 4.1% GDP while the US spends 17.3% and somehow does worse. Portugal decriminalized drugs and deaths dropped 94%. Norway rehabilitates prisoners and recidivism dropped to 20% vs America's 76%. All of this data is freely available. Policymakers remain committed to vibes-based governance. [View project](https://optimitron.com/) [GitHub](https://github.com/mikepsinn/optimitron) CLINICAL RESEARCH ### Decentralized FDA An open-source system for aggregating health data, analyzing it with causal-inference methods, and publishing reproducible evidence. The platform has generated 50,000+ observational studies from 12 million data points, meta-analyses for 90%+ of condition-treatment pairs, and treatment rankings for 100+ conditions. The goal is to make clinical discovery dramatically faster. At the current pace, testing the roughly 1.16 quadrillion possible drug combinations will finish in approximately never. [View project](https://dfda.earth/) [GitHub](https://github.com/decentralized-fda/decentralized-fda) [Browse Studies](https://studies.dfda.earth) GOVERNANCE MATH ### Wishocracy A governance mechanism called RAPPA that decomposes impossible budget decisions into simple pairwise slider comparisons. You spend 5-10 minutes doing \~20 comparisons. The eigenvector math does the rest. The US spends $886B on military vs $47B on NIH despite medical research having a 45:1 benefit-cost ratio vs military's 0.7:1\. When Porto Alegre let citizens set priorities, water access went from 75% to 98% and schools quadrupled. Taiwan used pairwise comparison tools to resolve a 4-year regulatory deadlock. The math works. The political will remains theoretical. [View project](https://wishocracy.warondisease.org/) [Try It](https://wishocracy.org/) [GitHub](https://github.com/mikepsinn/wishocracy) BOOK ### How to End War and Disease An instruction manual for humanity, narrated by an alien named Wishonia, on how to stop spending 40x more on building Skynet than on curing the diseases that are dissolving you. The alien has been watching your planet since 1945 and is very concerned. Free online; also in paperback, Kindle, and as an audiobook podcast. [View project](https://mikesinn.com/book) [Read Free](https://manual.WarOnDisease.org) [Amazon Paperback](https://warondisease.org/amazon/paperback) [Kindle](https://warondisease.org/amazon/kindle) [All Retailers](https://books2read.com/u/baegEq) [Spotify Audiobook](https://open.spotify.com/show/1aX8mw9MmFzyiSBq2RNnu2) [Apple Podcasts](https://podcasts.apple.com/us/podcast/how-to-end-war-and-disease/id1879755497) [YouTube](https://www.youtube.com/@WarOnDisease) [Goodreads](https://www.goodreads.com/book/show/248248875-how-to-end-war-and-disease) OPTIMISTIC SPREADSHEETS ### Global Survey on the 1% Treaty Redirect 1% of global military spending to health research. An estimated 416 million lives saved. 700× more effective than current spending. Sent to everyone with the power to implement it. Enthusiastically ignored. [View project](https://warondisease.org/) [GitHub](https://github.com/mikepsinn/disease-eradication-plan) SHOUTING INTO VOID ### Think by Numbers Data-driven policy analysis. Articles like 'The War on Drugs Increases Drug Deaths' and 'We Spend More on Corporate Welfare Than Social Welfare.' 2 million people read these. The policy remains exactly the same. [View project](https://thinkbynumbers.org/) [GitHub](https://github.com/mikepsinn/think-by-numbers) DAO ### CureDAO A DAO focused on clinical research. That's a lot of technical jargon, so let me translate: imagine if Wikipedia and a clinical trial had a baby that was raised by blockchain. The result is a platform where anyone can contribute to medical research without needing permission from a committee of very tired people in lab coats. [View project](https://curedao.org/) [GitHub](https://github.com/mikepsinn/curedao-monorepo) AI EXPERIMENT ### Wishonia An autonomous agent platform where AI tries to solve global problems. The agents are very enthusiastic. Their success rate is still being calculated. But they never sleep and they never complain, which is more than I can say for myself. [View project](https://wishonia.love/) [GitHub](https://github.com/mikepsinn/wishonia) PLATFORM ### Decentralized Institutes of Health A hub for digital health intelligence. Having multiple platforms seemed like a good idea at the time. The jury is still out. [View project](https://dih.earth/) MUSIC (LOOSELY DEFINED) ### The Plutonium Kidz The Plutonium Kidz were born of a secret government program involving the testing of plutonium exposure on human subjects. Through these experiments three normal children were thus transformed into the Plutonium Kidz! The government program, regrettably, remains classified. [View project](https://plutoniumkidz.mikesinn.com/) [GitHub](https://github.com/mikepsinn/plutonium-kidz) [SoundCloud](https://soundcloud.com/plutonium-kidz) ## Explore on GitHub All projects are open-source. Check out the code, contribute, or fork for your own use. [View GitHub profile](https://github.com/mikepsinn)